A study collecting information about people with mesothelioma of the lung (ASSESS-meso)

Cancer type:

Lung cancer

Mesothelioma

Status:

Open

Phase:

Other

The researchers want to know more about people who have mesothelioma, their symptoms and how it affects their life.

Mesothelioma can affect the lining around the:

lungs
heart
tummy (abdomen)

This study is for people with mesothelioma of the lung.

More about this trial

Mesothelioma of the lung is difficult to treat. Researchers are looking for better treatments and how to improve care for people with mesothelioma.

In this study they will collect information about:

your quality of life
any symptoms you have

They will also collect medical information including:

blood samples
any tests you might have

Mesothelioma can cause fluid to build up between the sheets of tissue that surround your lung. Treatment for this is to drain the fluid off. The researchers also want to collect samples of this fluid.

The team will use this information to:

find out more about mesothelioma
improve the care for people with mesothelioma

The main aim of this study is to gather information about people with mesothelioma.

Another aim of this study is to identify and invite selected people with mesothelioma who might be able to take part in a clinical trial.

Who can enter

The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.

Who can take part

You may be able to join this study if you:

have mesothelioma of the lung
are at least 18 years old

Who can’t take part

You cannot join this study if you have decided not to have ongoing follow up at the hospital.

Trial design

The team need about 700 people to join the study.

When you join the study you:

fill in a quality of life questionnaire
are asked how bad your symptoms are
have blood tests taken
have a chest x-ray
have a CT scan of your chest
have an ultrasound of your chest

At every routine appointment afterwards you:

fill in a quality of life queationnaire
are asked how bad your symptoms are

And if needed you:

have blood tests taken
have a chest x-ray
have a CT scan of your chest
have an ultrasound of your chest

If you are having some fluid drained from the sheets of tissue between your lung, the team will ask for a sample. Or if you have a tube in place that drains the fluid they will ask for a sample of the fluid.

Hospital visits

The questionnaires and tests are done as part of your routine hospital appointments. So your routine hospital appointments will take longer.

The team won’t ask you to have extra visits to the hospital unless it is really necessary.

Side effects

As part of the study you might have extra scans and x-rays.

These tests use radiation that can cause damage to your cells. And might increase your chances of another cancer. This usually takes years or decades to happen if it does.

The amount of extra radiation from these extra scans and x-rays is the same as the amount of 6 years of natural radiation. This is radiation that occurs naturally and can be found all around us. For example, in soil and rocks.

Location

Bath

Bristol

Cambridge

Cardiff

Carmarthen

Chelmsford

Derby

Glasgow

Leicester

Manchester

Newcastle upon Tyne

Oxford

Plymouth

South Shields

Sutton in Ashfield

Taunton

Recruitment start:

31/05/2017

Recruitment end:

31/05/2027

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

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Questions to ask your doctor about clinical trials

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Anna Bibby

Supported by

Avon Mesothelioma Foundation
North Bristol NHS Trust
University of Bristol

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Email

Last review date

1 June 2022

CRUK internal database number:

15701