Central lines

You might have chemotherapy into the bloodstream through a long flexible plastic tube called a central line. 

They are called central lines because they end up in a central blood vessel in your chest, close to your heart.

Diagram showing a central line

There are different types of central line:

  • acute central line

  • tunnelled central line

  • peripherally inserted central catheter (PICC line)

  • portacath or totally implantable venous access device (TIVAD)

This page is about acute and tunnelled central lines.

Acute central lines

An acute central line goes in through a vein in your neck. It is used for short term treatments. You might have one if you need treatment urgently or it is difficult to find a vein for a cannula.

Skin tunnelled central lines

A skin tunnelled central line goes in through your chest. It goes under your skin and into a large vein by your collarbone. The only bit you can see is the length of line that hangs out of the small entry hole in your chest. 

At the end of the length of line that you can see, there are connection ports where the nurse attaches your chemotherapy. The connection ports are kept closed with caps.

This is a picture of a skin tunnelled central line in place.

Photograph of a central line

Before a skin tunnelled line is inserted, you have a local or general anaesthetic. Sometimes doctors use continuous x-rays as they put the tube in, so they can see where it’s going. Your doctor may want you to have an x-ray afterwards to make sure the end of the tube is in the best place.

When the tunnelled line is in, they will stitch it in place or put special dressings over it, so it can't come out. The stitches are removed after about a week. There is also a small cuff on the line, which is under the skin and holds it in place. You can move about normally. It won't come out while you’re sleeping or dressing.

The tunnelled line can stay in your vein for many months. So you won't need to have needles into your hand or arm each time you have your chemotherapy treatment.

Your doctor and nurse can also take blood from the line for tests. They can also use the line to give you fluids or other treatment such as antibiotics if you need them.

The video below shows how a tunnelled central line is put in. It is 1 minute and 47 seconds long. 

Possible problems

Sometimes problems can happen with tunnelled central lines:

  • you may get an infection

  • the line may get blocked

  • a blood clot can develop

  • the line may split, but this is very rare

Your nurse will test your tunnelled central line each time they use it. They will check for blood return and inject it with salt water (saline). This is called flushing. It’s very important to tell your nurse if you experience pain as the line is flushed or during chemotherapy. This could mean the line has split.

If you are not having treatment regularly, you or your nurse needs to clean and flush the line weekly. This will keep it clear and stop any problems developing. It is flushed with heparin Open a glossary item and saline to clean the line and prevent clotting. The nurses on the ward can teach you or your carer how to do this. Your district nurse can care for your line or help you at home at first.

It’s very important to avoid getting an infection in the area where your line goes into your body. Speak to your chemotherapy nurse or doctor if you notice any redness, swelling, oozing or soreness. These could be signs of infection.

You’ll need to have treatment with antibiotics straight away if you do develop an infection. Otherwise, a doctor or nurse may have to remove the line and put a new one in.

Everyday life with a central line

You can go home with a central line in place. There are very few restrictions to your everyday life.

It’s fine to have a bath or shower. Don't let your line go under water in the bath.

Before you go home, make sure you’re confident about looking after your line. Ask the staff on the ward if you’re not sure about anything. They can arrange for district nurses to visit you at home to help with the line until you feel confident.

Contact your advice line if you have any problems at home.

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    Royal College of Nursing, 2016

  • Central venous access in oncology: ESMO clinical practice guidelines
    B Sousa and others
    Annals of Oncology, 2015. Volume 26. Pages V152-V168

  • Cancer: Principles and practice of oncology (12th edition)
    VT De Vita, TS Lawrence and SA Rosenberg 
    Wolters Kluwer, 2023

  • Cancer Chemotherapy in Clinical Practice (2nd edition)
    T Priestman
    Springer, 2012

  • Handbook of Cancer Chemotherapy (8th edition)
    R T Skeel and S N Khleif
    Lippincott, Williams and Wilkins, 2015

  • The Royal Marsden Hospital Manual of Clinical and Cancer Nursing Procedures (10th edition, online)
    S Lister, J Hofland and H Grafton
    Wiley Blackwell, 2020

Last reviewed: 
16 May 2024
Next review due: 
17 May 2027

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