A study looking at helping men manage the side effects of treatment for prostate cancer (MANCAN)
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This study looked at managing hot flushes and night sweats caused by hormone therapy for prostate cancer.
The study was open for people to join between 2012 and 2013. The team published the results in 2015. There is a link to more information in the ‘Summary of results’ section below.
More about this trial
Hormone therapy is one of the treatments for prostate cancer. It can cause side effects such as hot flushes and night sweats, which affect people’s quality of life.
In this study, researchers wanted to help men manage these side effects by learning how to use cognitive behavioural therapy (CBT). At the time, standard care was for men to speak to a health care professional for advice if they wanted to.
Everyone taking part in this study was having side effects caused by hormone therapy for prostate cancer. They were put into a treatment group at random:
- half had standard care
- half were taught how to do self guided CBT
The CBT group were given a detailed booklet and a relaxation CD. They also had phone calls with a
Everyone taking part:
- had an interview with a researcher
- completed a questionnaire about their quality of life
- wore a hot flush monitor for up to 48 hours
The main aim of this study was to find out if CBT can help manage hot flushes and night sweats caused by treatment for prostate cancer.
Summary of results
We aim to add a lay summary of results to all the studies on our database. Unfortunately we have not been able to include a summary for this one.
There is more information about the results in the link below.
A randomised controlled trial of a brief cognitive behavioural intervention for men who have hot flushes following prostate cancer treatment (MANCAN)
E Stefanopoulou and others
Psycho oncology, 2015. Volume 24, issue 9, pages 1159–1166.
Please note, the information we link to here is not in plain English. It has been written for healthcare professionals and researchers.
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Professor Myra Hunter
Supported by
Guy's and St Thomas' NHS Foundation Trust
NIHR Clinical Research Network: Cancer
Prostate Cancer UK
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040